Understanding Paracetamol Use During Pregnancy: What You Need to Know

The Link Between Paracetamol and Autism Spectrum Disorder

Recent media headlines from the United States have sparked concern about a possible link between paracetamol use during pregnancy and autism spectrum disorder (ASD). Understandably, this has left many parents and parents-to-be feeling worried. So, what does the evidence really say? As health professionals, let’s look past the headlines and into the science.

What Does the Science Say about Paracetamol and Pregnancy?

• The current scientific consensus does not support a causal link between paracetamol and autism.

• Some observational studies have suggested a possible association, but these studies have important limitations. Many other factors, such as maternal illness, genetics, and environmental influences, are involved.

• In other words, these studies do not prove that paracetamol causes autism.

  
  

What is the TGA’s Position?

In Australia, the Therapeutic Goods Administration (TGA) continues to classify paracetamol as Pregnancy Category A — meaning it is considered safe for use during pregnancy when used as directed. As of September 2025, there are no active safety investigations into paracetamol and autism or other neurodevelopmental disorders.

Why Is This in the News Again?

Recent statements by US officials and media outlets have reignited public scrutiny of paracetamol’s safety in pregnancy. However, Australian experts caution against alarm, emphasising that paracetamol has been used safely for decades and remains the first-line option for pain and fever relief during pregnancy.

Should Pregnant Women Avoid Paracetamol?

No. Paracetamol remains the first-choice medicine for managing pain and fever during pregnancy. The key is safe use:

1. Use the lowest effective dose.

2. For the shortest possible duration.

3. If you are unsure, consult your GP, obstetrician, or pharmacist.

   
   

The Importance of Pain Management During Pregnancy

Managing pain and fever is crucial during pregnancy. Uncontrolled pain can lead to stress and complications for both the mother and the baby. It’s essential to address these issues promptly and safely.

When to Seek Help

If you experience persistent pain or fever, don’t hesitate to reach out to your healthcare provider. They can help you determine the best course of action. Remember, it’s always better to ask questions than to suffer in silence.

Key Takeaway

While headlines may sound worrying, the best available evidence supports the safe use of paracetamol in pregnancy. Fever and uncontrolled pain themselves can pose risks to both mother and baby — so avoiding treatment out of fear may not be the safest choice. 👉 If you are pregnant and have questions about using paracetamol or any other medicine, always check with your trusted healthcare professional.

❓ FAQ: Paracetamol and Pregnancy

Does paracetamol cause autism? 👉 No. Current research does not show a causal link between paracetamol use in pregnancy and autism. Some studies suggest possible associations, but these are limited and cannot prove cause and effect.

Is Panadol safe during pregnancy? 👉 Yes. When used as directed, Panadol (paracetamol) remains the first-choice option for pain and fever relief during pregnancy.

What is Pregnancy Category A? 👉 In Australia, Pregnancy Category A means the medicine has been taken by a large number of pregnant women without any proven increase in harmful effects on the baby. Paracetamol is listed in this category.

Conclusion

In summary, the evidence surrounding paracetamol use during pregnancy is reassuring. While it’s natural to feel concerned about new research, it’s important to rely on established guidelines and the advice of healthcare professionals. By staying informed and seeking help when needed, you can ensure a safer pregnancy experience. Remember, you are not alone in this journey. Your health and the health of your baby are paramount, and there are resources available to support you every step of the way.

⚠️ Disclaimer

This content is for general information purposes only and should not be taken as personal medical advice. It is not a substitute for consultation with a qualified health professional. If you are pregnant or have concerns about medicines and your health, please seek advice from your doctor or pharmacist.

📚 References

• Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG). Guidelines on Analgesia in Pregnancy.

• Australian Medicines Handbook. 2025 Edition.

• Therapeutic Goods Administration (TGA). Medicines and safety information